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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 7, 2012; 18(45): 6577-6586
Published online Dec 7, 2012. doi: 10.3748/wjg.v18.i45.6577
Published online Dec 7, 2012. doi: 10.3748/wjg.v18.i45.6577
Table 3 Frequencies of phosphatidylinositol 3-kinase, catalytic, alpha polypeptide mutations detected in gastric cancer tissues
| Mutation | Overall frequency | Percent/total cases | Percent/mutated cases | Microsatellite instability | |
| Exon1 | R88Q | 1 | 0.4 | 5 | 1 |
| R108H | 4 | 1.7 | 20 | 1 | |
| Total | 5 | 2.2 | 2 | ||
| Exon9 | E542K | 5 | 2.2 | 25 | 1 |
| E545K | 2 | 0.9 | 10 | 1 | |
| E545G | 2 | 0.9 | 10 | 1 | |
| Total | 9 | 4.0 | 3 | ||
| Exon20 | H1047Y | 1 | 0.4 | 5 | 1 |
| H1047R | 6 | 2.6 | 30 | 4 | |
| Total | 7 | 3.0 | 5 |
- Citation: Sukawa Y, Yamamoto H, Nosho K, Kunimoto H, Suzuki H, Adachi Y, Nakazawa M, Nobuoka T, Kawayama M, Mikami M, Matsuno T, Hasegawa T, Hirata K, Imai K, Shinomura Y. Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer. World J Gastroenterol 2012; 18(45): 6577-6586
- URL: https://www.wjgnet.com/1007-9327/full/v18/i45/6577.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i45.6577