Eosinophil associated genes in the inflammatory bowel disease 4 region: Correlation to inflammatory bowel disease revealed

Table 3 Genotype and allelic frequency distribution among 300 healthy individuals and the total cohorts of Crohn’s disease and ulcerative colitis

	GG-genotype (%)	GC-genotype (%)	CC-genotype (%)	G-allele (%)	C-allele (%)
Healthy
ECP562	68	29	3	83	17
ECP434	57	38	5	76	24
EPX405 M1	64	32	4	80	20
EPX405 F1	53	38	9	72	28
CD
ECP562	64	33	4	80	20
ECP434	53	40	7	73	27
EPX405 M	55	38	6	74	26
EPX405 F	58	34	8	75	25
UC
ECP562	64	33	4	80	20
ECP434	55	38	7	74	26
EPX405 M	62	31	7	78	22
EPX405 F	57	38	5	76	24

For ECP434 and ECP562 there was no difference between males and females.

¹In EPX405 there was a difference between the sexes according their genotype (P = 0.049) and allelic distribution (P = 0.021). UC: Ulcerative colitis; CD: Crohn’s disease; EPX: Eosinophil protein X; ECP: Eosinophil cationic protein; F: Female; M: Male.