Lymphangioma of the small bowel mesentery: A case report and review of the literature

Figure 3 Histopathology. A: Cystic spaces (asterisks) with smooth muscle in their walls (hematoxyin and eosin, 40 ×); B: Flat lining cells of the cystic spaces with smooth muscle below them (hematoxyin and eosin, 400 ×); C: Lymphatic spaces in the stroma containing lymphoid cells (arrow) and pale eosinophilic fluid, suggestive of lymph (asterisks) (hematoxyin and eosin, 200 ×); D: Subendothelial lymphoid follicle (hematoxyin and eosin, 200 ×); E-G: Immunohistochemical study of the lining cells of the cystic wall shows strong cytoplasmic immunoreactivity for factor VIII-related antigen (E, 600 ×) and focal reactivity with D2-40 (F, 1000 ×, arrows) but not for calretinin (G, 600 ×); H: Immunohistochemical study for human melanoma black-45 shows negative result in the smooth muscle of the lymphatic wall (100 ×).