Durability of viral response after off-treatment in HBeAg positive chronic hepatitis B

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Nov 21, 2012 (publication date) through Jul 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2012; 18(43): 6277-6283
Published online Nov 21, 2012. doi: 10.3748/wjg.v18.i43.6277

Table 3 Clinical characteristics in virological recurrence and non-recurrence

	Virological recurrence(n = 20)	Virological non-recurrence(n = 28)	P value
Age, yr (mean ± SD)	46.7 ± 12.1	38.8 ± 12.7	0.022
Sex (male/female)	11/9	29/19	0.561
Pretreatment ALT level (IU/L)	199 (40-374)	189 (11-364)	0.491
Pretreatment HBV DNA level (log₁₀ copies/mL)	7.7 (5.1-10)	7 (5.0-9.1)	0.125
Time to undetectable HBV (mo)	6.7 (2.3-39.4)	9.1 (1.3-25.0)	0.490
Time to HBeAg seroconversion (mo)	13.9 (0.8-39.4)	12.7 (1.4-31.2)	0.744
Consolidation treatment duration (mo)	10.3 (6-23.9)	11.7 (6-37.9)	0.517
Total treatment duration (mo)	25.6 (9.6-47.4)	27.0 (9.4-43.3)	0.358
Antiviral agent (entecavir/clevudine)	15/5	16/12	0.236

ALT: Alanine aminotransferase; HBV: Hepatitis B virus; HBeAg: Hepatitis B e antigen.

Citation: Song MJ, Song DS, Kim HY, Yoo SH, Bae SH, Choi JY, Yoon SK, Paik YH, Lee JS, Lee HW, Kim HJ. Durability of viral response after off-treatment in HBeAg positive chronic hepatitis B. World J Gastroenterol 2012; 18(43): 6277-6283
URL: https://www.wjgnet.com/1007-9327/full/v18/i43/6277.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i43.6277