Quasispecies dynamics in main core epitopes of hepatitis B virus by ultra-deep-pyrosequencing

Table 1 Baseline characteristics of the four patients included in the study

Patient	Sex	Age (yr)	ALT (IU/mL)	HBV DNA (log10 IU/mL)	Genotype	HBeAg status
1	Male	46	167	7.4	A	-1
2	Male	39	95	7.8	A	+
3	Male	31	392	8.3	D	-
4	Female	55	117	7.5	D	-

Age at the time of sample collection.

¹Wild type in main precore mutation. ALT: Alanine transaminase; HBeAg: Hepatitis B e antigen; HBV: Hepatitis B virus.