Drug-induced liver injury in hospitalized patients with notably elevated alanine aminotransferase

Table 1 Characteristics of patients with alanine aminotransferase > 10 upper limit of normal range (mean ± SD)

Causes	n (%)	Age (yr)	Female n (%)	Peak ALT values (× ULN)
Hemodynamic injury	46 (25.7)	54.2 ± 17.2a	14 (30.4)	32.5 ± 30.7b
Drug-induced liver injury	25 (19.4)	45.4 ± 16.8	9 (36.0)	14.5 ± 5.6
Malignancy	21 (16.3)	55.8 ± 14.6a	2 (9.5)	17.5 ± 10.3
Biliary abnormality	15 (11.6)	52.3 ± 14.4	7 (46.7)	14.3 ± 7.7
Viral hepatitis	12 (9.3)	47.8 ± 16.8	4 (33.3)	18.6 ± 10.0
Undetermined and others	10 (7.8)	42.9 ± 12.0	5 (50)	30.9 ± 33.5a
Total	129 (100)	51.1 ± 16.4	41 (31.8)	23.0 ± 22.7
P (between different causes)	-	0.085	0.15	0.004

Post hoc tests

^aP < 0.05,

^bP < 0.01 vs drug-induced liver injury group. ALT: Alanine aminotransferase; ULN: Upper limit of normal range.