Correlation between mitochondrial TRAP-1 expression and lymph node metastasis in colorectal cancer

Table 1 Relationship between tumor necrosis factor receptor-associated protein-1 expression and clinicopathological factors in colorectal cancer

Clinicopathological factors	n	TRAP-1 expression		P value1
		Negative	Positive
Sex
Male	46	16	30	0.225
Female	50	23	30
Age (yr)
≤ 60	66	30	36	0.486
> 60	30	10	20
Tumor size (cm)
≤ 5	70	30	40	0.065
> 5	26	11	15
Tumor location
Colon	31	11	20	0.915
Rectum	65	32	33
Tumor differentiation2
I-II	80	45	35	0.212
III-IV	16	6	10
Tumor status2
T1-2	34	14	20	0.512
T3-4	62	31	31
Lymph node metastasis2
N0	45	35	10	< 0.001
N1-2	51	5	46
TNM stage2
I-II	41	30	11	< 0.001
III-IV	55	6	49

¹Statistical analysis was performed with χ² test;

²Grading of differentiation status and tumor node metastasis (TNM) classification for colorectal cancer were based on the American Joint Committee on Cancer: Cancer Staging Manual (7th edition, 2009). The tumors were classified into two groups: Well differentiated (grades I and II) and poorly differentiated (grades III and IV).