Liver cold preservation induce lung surfactant changes and acute lung injury in rat liver transplantation

Figure 2 Serum NO, ET-1 level and lung weight/body weight ratio. A: NO levels in different groups. With CPT prolonged, NO level decreased significantly, and became even lower with PDTC injection post-reperfusion; B: ET-1 level in different groups. With CPT prolonged, ET-1 level increased significantly compared with the sham group. The PDTC group had a significantly lower ET-1 level than 180-min group; C: Lung weight/body weight ratios in different groups. The ratios increased compared with the sham group. Significant difference was observed between the 180-min group and PDTC group. ^aP < 0.05 vs sham group; ^bP < 0.05 vs 45-min group; ^cP < 0.05 vs PDTC group. PDTC: Pyrrolidinedithiocarbamate; CPT: Cold preservation time; NO: Nitric oxide; ET: Endothelin.