MUC5AC/β-catenin expression and KRAS gene alteration in laterally spreading colorectal tumors

Figure 2 Immunoreactive scores for MUC2, MUC5AC, MUC6 and CD10 in all (A, D, G, J), proximal (B, E, H, K) and distal (C, F, I, L) laterally spreading tumors. Gr, Gr-LST (black bar); NGr, NGr-LST (white bar). IRS: Immunoreactive score; LGD: Adenoma with low grade dysplasia; HGD: Adenoma with high grade dysplasia; INV: Adenocarcinoma invading into submucosa; LSTs: laterally spreading tumors; Gr: Granular; NGr: Non-granular. Data are mean ± SD; ^{a, c, e, g, i, k, m, o, q, s, u, w, y}P < 0.05, MUC2: all NGr-HGD vs NGr-INV; proximal colon NGr-LGD vs NGr-HGD or NGr-INV; Gr-LGD vs Gr-HGD; distal colon Gr-LGD vs Gr-INV; NGr-HGD vs NGr-INV; MUC5AC: all Gr-LGD vs Gr-INV; distal colon NGr-INV vs NGr-HGD or NGr-LGD; MUC6: proximal colon NGr-INV vs NGr-LGD or NGr-HGD; CD10: all NGr-LGD vs NGr-HGD; proximal colon NGr-LGD vs NGr-HGD; ^{b, d, f, h, j, l, n, p, r, t}P < 0.01, MUC2: all Gr-LGD vs Gr-HGD or Gr-INV; NGr-LGD vs NGr-INV; proximal colon Gr-LGD vs Gr-INV; distal colon Gr-LGD vs Gr-HGD; MUC5AC: all Gr-LGD vs NGr-LGD; Gr-LGD vs Gr-HGD; proximal colon Gr-type vs NGr-type; Gr-LGD vs NGr-LGD; Gr-LGD vs Gr-INV.