MUC5AC/&beta;-catenin expression and KRAS gene alteration in laterally spreading colorectal tumors

doi:10.3748/wjg.v18.i39.5551

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 39

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6241)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-6) series, Tables (1-3) series.

Item

Count

PDF

429

HTML

5421

Figures (1-6)

217

Tables (1-3)

174

Sum=6241

Oct 21, 2012 (publication date) through Jul 28, 2024

Times Cited of This Article

Times Cited (7)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Original Article

World J Gastroenterol. Oct 21, 2012; 18(39): 5551-5559
Published online Oct 21, 2012. doi: 10.3748/wjg.v18.i39.5551

Table 3 Frequency of KRAS and BRAF mutations in laterally spreading tumor of the colorectum

Type of tumors	Number (%) of mutated samples
	All			Proximal colon
	n	KRAS	BRAF	n	KRAS
Gr-type	29	15 (52)^a	2 (7)	13	9 (69)^c
LGD	10	6 (60)	0 (0)	7	6 (86)^d,e
HGD	10	6 (60)^b	1 (10)	3	2 (67)
INV	9	3 (33)	1 (11)	3	1 (33)
NGr-type	27	2 (7)^a	0 (0)	18	1 (6)^c
LGD	10	1 (10)	0 (0)	8	1 (13)^d
HGD	10	0 (0)^b	0 (0)	8	0 (0)
INV	7	1 (14)	0 (0)	2	0 (0)
Total	56	17 (30)	2 (4)	30	10 (33)

Gr-type: Granular type of laterally spreading tumor; NGr-type: Flat- or non-granular type of laterally spreading tumor; LGD: Adenoma with low grade dysplasia; HGD: Adenoma with high grade dysplasia; INV: Adenocarcinoma invading submucosa; KRAS: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; BRAF: v-raf murine sarcoma viral oncogene homologue B1. ^{a, c, e}P < 0.05, All and proximal colon: Gr-type vs NGr-type; Gr-LGD: proximal vs distal colon; ^{b, d}P < 0.01, all and proximal colon: Gr-HGD vs NGr-HGD; proximal colon: Gr-type vs NGr-type.

Citation: Nakae K, Mitomi H, Saito T, Takahashi M, Morimoto T, Hidaka Y, Sakamoto N, Yao T, Watanabe S. MUC5AC/β-catenin expression and KRAS gene alteration in laterally spreading colorectal tumors. World J Gastroenterol 2012; 18(39): 5551-5559
URL: https://www.wjgnet.com/1007-9327/full/v18/i39/5551.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i39.5551