Identification of deregulated miRNAs and their targets in hepatitis B virus-associated hepatocellular carcinoma

Table 2 Deregulated miRNA in hepatitis B virus-associated hepatocellular carcinoma n (%)

miRNA	Fold change	P value	Validation1
Up-regulated miRNAs
hsa-miR-520g	9475.09	0.00	13 (72.2)
hsa-miR-519a	8204.48	0.00	10 (55.6)
hsa-miR-522	6178.34	0.00	13 (72.2)
hsa-miR-518e	4096.74	0.00	11 (61.1)
hsa-miR-525-3p	1489.49	0.00	14 (77.8)
hsa-miR-217	1080.33	0.00	11 (59.4)
hsa-miR-518b	982.85	0.00	14 (77.8)
hsa-miR-512-3p	197.21	0.00	10 (55.6)
hsa-miR-517c	130.92	0.00	11 (61.1)
hsa-miR-518a-3p	46.84	0.00	10 (55.6)
Down-regulated miRNAs
hsa-miR-199a-5p	0.00237	0.00050	13 (72.2)
hsa-miR-433	0.00310	0.00270	10 (55.6)
hsa-miR-592	0.01137	0.00350	11 (59.4)
hsa-miR-214#	0.01327	0.00610	11 (59.4)
hsa-miR-483-5p	0.03310	0.00340	14 (77.8)
hsa-miR-483-3p	0.03323	0.00510	12 (72.2)
hsa-miR-138	0.03727	0.00190	14 (77.8)
hsa-miR-214	0.04213	0.00530	11 (59.4)
hsa-miR-511	0.07957	0.00490	13 (72.2)
hsa-miR-708	0.02135	0.00480	10 (55.6)
hsa-miR-1275	0.06296	0.00530	10 (55.6)

¹Quantitative reverse-transcription polymerase chain reaction was performed in 18 pairs of tumor and non-tumor tissues in hepatitis B virus-associated hepatocellular carcinoma.