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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 14, 2012; 18(38): 5418-5426
Published online Oct 14, 2012. doi: 10.3748/wjg.v18.i38.5418
Published online Oct 14, 2012. doi: 10.3748/wjg.v18.i38.5418
Table 5 Prevalence of pre-S mutations in hepatitis B e antigen (-) and hepatitis B e antigen (+) associated with progressive liver disease
| Mutation | HBeAg(-) | HBeAg(+) | ||||||||||
| AC | CH | LC | HCC | All | P-value | AC | CH | LC | HCC | All | P-value | |
| n = 46 | n = 28 | n = 41 | n = 38 | n = 155 | n = 13 | n = 36 | n = 18 | n = 15 | n = 82 | |||
| M12 | 0 (0.0) | 10 (35.7) | 17 (41.5) | 9 (23.7) | 36 (23.5) | < 0.001 | 0 (0.0) | 2 (5.6) | 7 (38.9) | 6 (40.0) | 15 (18.3) | < 0.001 |
| T130 | 6 (13.0) | 10 (35.7) | 11 (26.8) | 13 (34.2) | 40 (26.1) | 0.082 | 2 (15.4) | 9 (25.0) | 6 (33.3) | 6 (40.0) | 23 (28.0) | 0.474 |
| Q13 | 6 (13.0) | 10 (35.7) | 12 (29.3) | 14 (36.8) | 42 (27.5) | 0.057 | 3 (23.1) | 9 (25.0) | 8 (44.4) | 6 (40.0) | 26 (31.7) | 0.389 |
| A13 | 6 (13.0) | 10 (35.7) | 13 (31.7) | 13 (34.2) | 42 (27.5) | 0.072 | 2 (15.4) | 11 (30.6) | 8 (44.4) | 6 (40.0) | 27 (32.9) | 0.344 |
- Citation: Utama A, Siburian MD, Fanany I, Intan MDB, Dhenni R, Kurniasih TS, Lelosutan SA, Achwan WA, Zubir N, Arnelis, Lukito B, Yusuf I, Lesmana LA, Sulaiman A. Hepatitis B virus pre-S2 start codon mutations in Indonesian liver disease patients. World J Gastroenterol 2012; 18(38): 5418-5426
- URL: https://www.wjgnet.com/1007-9327/full/v18/i38/5418.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i38.5418