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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 14, 2012; 18(38): 5418-5426
Published online Oct 14, 2012. doi: 10.3748/wjg.v18.i38.5418
Published online Oct 14, 2012. doi: 10.3748/wjg.v18.i38.5418
Table 3 Prevalence of pre-S mutations in hepatitis B virus genotype B and C associated with progressive liver disease
| Mutations | Genotype B | Genotype C | ||||||||||
| AC | CH | LC | HCC | All | P-value | AC | CH | LC | HCC | All | P-value | |
| n = 56 | n = 46 | n = 46 | n = 52 | n = 200 | n = 17 | n = 20 | n = 20 | n = 12 | n = 68 | |||
| M120 | 1 (1.8) | 8 (17.4) | 21 (45.7) | 16 (30.8) | 46 (23.0) | < 0.001 | 1 (5.9) | 4 (20.0) | 6 (30.0) | 2 (16.7) | 13 (19.1) | 0.324 |
| T130 | 6 (10.7) | 11 (23.9) | 10 (21.7) | 19 (36.5) | 46 (23.0) | 0.017 | 2 (11.8) | 8 (40.0) | 8 (40.0) | 6 (50.0) | 24 (35.3) | 0.098 |
| Q132 | 9 (16.1) | 11 (23.9) | 12 (26.1) | 20 (38.5) | 52 (26.0) | 0.067 | 2 (11.8) | 8 (40.0) | 9 (45.0) | 6 (50.0) | 25 (36.8) | 0.081 |
| A138 | 8 (14.3) | 12 (26.1) | 13 (28.3) | 20 (38.5) | 53 (26.5) | 0.042 | 2 (11.8) | 9 (45.0) | 9 (45.0) | 6 (50.0) | 26 (38.2) | 0.070 |
- Citation: Utama A, Siburian MD, Fanany I, Intan MDB, Dhenni R, Kurniasih TS, Lelosutan SA, Achwan WA, Zubir N, Arnelis, Lukito B, Yusuf I, Lesmana LA, Sulaiman A. Hepatitis B virus pre-S2 start codon mutations in Indonesian liver disease patients. World J Gastroenterol 2012; 18(38): 5418-5426
- URL: https://www.wjgnet.com/1007-9327/full/v18/i38/5418.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i38.5418