Nur-related receptor 1 gene polymorphisms and alcohol dependence in Mexican Americans

Table 3 Genotype and allele frequency of the -1198(C/G) allele in Mexican American alcoholics and non-alcoholics controlling for confounding effect of smoking and obesity n (%)

Groups	Genotype			Allele frequency
	C/C	C/G	G/G	C
Non-alcoholic
BMI < 30 kg/m2 (199)	54 (27.1)	81 (40.7)	64 (32.2)	189 (47.5)
BMI ≥ 30 kg/m2 (115)	21 (18.3)	62 (53.9)	32 (27.8)	104 (45.2)
Alcoholic
BMI < 30 kg/m2 (181)	26 (14.4)	92 (50.8)	63 (34.8)a	144 (39.8)b
BMI ≥ 30 kg/m2 (136)	18 (13.2)	73 (53.7)	45 (33.1)	109 (40.1)
Non-alcoholic
Non-smokers (265)	61 (23.0)	122 (46.0)	82 (30.9)	244 (46.0)
Smokers (55)	15 (18.3)	24 (53.9)	16 (27.8)	54 (49.1)
Alcoholic
Non-smokers (185)	27 (14.6)	90 (48.6)	68 (36.8)	144 (38.9)c
Smokers (161)	21 (13.0)	86 (53.4)	54 (33.5)d	128 (39.7)

^aP = 0.008 vs nonalcoholic body mass index (BMI) < 30 kg/m²;

^bP = 0.032 vs nonalcoholic BMI < 30 kg/m²;

^cP = 0.034 vs nonalcoholic non-smokers;

^dP = 0.05 vs non-alcoholic smokers.