Nur-related receptor 1 gene polymorphisms and alcohol dependence in Mexican Americans

Table 2 Genotype and allele frequency of the -2922(C)2-3 allele in Mexican American alcoholics and non-alcoholics controlling for confounding effect of smokers and obesity n (%)

Groups	Genotype			Allele frequency
	(C)2/(C)2	(C)2/(C)3	(C)3/(C)3	(C)3
Non-alcoholic
BMI < 30 kg/m2 (213)	73 (34.3)	78 (36.6)	62 (29.1)	202 (47.4)
BMI ≥ 30 kg/m2 (122)	41 (33.6)	48 (39.3)	33 (27.0)	114 (46.7)
Alcoholic
BMI < 30 kg/m2 (198)	37 (18.7)	107 (54.0)	54 (27.3)a	215 (54.3)b
BMI ≥ 30 kg/m2 (146)	37 (21.5)	74 (50.7)	35 (25.9)	144 (49.3)
Non-alcoholic
Non-smokers (282)	100 (35.5)	101 (35.8)	81 (28.7)	263 (46.6)
Smokers (59)	17 (28.8)	29 (49.2)	13 (22.0)	55 (46.6)
Alcoholic
Non-smokers (197)	49 (24.9)	88 (44.7)	60 (30.5)c	208 (52.8)
Smokers (177)	38 (21.5)	104 (58.8)	35 (19.8)d	174 (49.2)

^aP = 0.000 vs nonalcoholic body mass index (BMI) < 30 kg/m²;

^bP = 0.049 vs nonalcoholic BMI < 30 kg/m²;

^cP = 0.037 vs non-alcoholic non-smokers;

^dP = 0.016 vs alcoholic non-smokers.