Contrast-enhanced ultrasound evaluation of hepatic microvascular changes in liver diseases

Table 2 Contrast-enhanced ultrasonography parameters calculated with Qontrast software in the three study groups (mean ± SD)

Perfusion parameter	Controls		Non-cirrhotic patients		Cirrhotic patients
	ROI with HV	ROI without HV	ROI with HV	ROI without HV	ROI with HV	ROI without HV
TTP (s)	86.3 ± 20.3	86.8 ± 24.9	82.4 ± 15.6	78.2 ± 12.0	71.0 ± 11.3a	73.7 ± 17.8
Peak (%)	18.9 ± 7.1	18.5 ± 7.8	25.9 ± 7.8c	23.1 ± 8.9	23.9 ± 5.9e	25.5 ± 6.6
RBV	2828.7 ± 1720	2827.4 ± 1642.1	3402.3 ± 1515.1	2734.9 ± 1327.5	2809.3 ± 1111.6	3031.9 ± 1000.2
RBF	21.4 ± 9.5	21.4 ± 10.5	29.3 ± 10.5	25.6 ± 11.1	27.2 ± 7.9	28.8 ± 8.1
MTT (s)	139.4 ± 39.8	128.4 ± 37.8	110.3 ± 14.6c	105.8 ± 17.1c	111.9 ± 22.0c	104.7 ± 24.4c

MTT: Mean transit time; RBV: Regional blood volume; RBF: Regional blood flow; TTP: Time to peak; ROI: Region of interest; HV: Hepatic vein.

^aP < 0.05 vs other groups;

^cP < 0.05 vs control group;

^eP = 0.05 vs control group.