Effectiveness of infliximab after adalimumab failure in Crohn's disease

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 37

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

All Articles published online

Item

Count

PDF

345

HTML

1747

Tables (1-2)

166

Sum=2258

Oct 7, 2012 (publication date) through Nov 5, 2024

Times Cited of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Brief Article

World J Gastroenterol. Oct 7, 2012; 18(37): 5219-5224
Published online Oct 7, 2012. doi: 10.3748/wjg.v18.i37.5219

Table 2 Responses to the switch from adalimumab to infliximab

Reason for ADA discontinuation	Indication for anti-TNF	Initial response to ADA	Final response to ADA	ADA escalation	Initial response to ADA escalation	Final response to ADA escalation	Initial response to IFX	AE with IFX
Loss of response	Perianal	Partial response	No response	No	NA	NA	Remission	No
Loss of response	Luminal	Remission	No response	No	NA	NA	Remission	No
Loss of response	Luminal	Partial response	No response	Yes	Partial response	No response	Remission	No
Loss of response	Luminal	Partial response	Partial response	Yes	No response	NA	Partial response	No
Loss of response	Luminal	Partial response	No response	Yes	No response	NA	Partial response	No
Partial response	Luminal	Partial response	Partial response	No	NA	NA	Partial response	No
Partial response	Perianal	Partial response	No response	Yes	Partial response	Partial response	Partial response	No
Partial response	Luminal	Partial response	Partial response	No	NA	NA	Partial response	No
Partial response	Luminal	Partial response	Partial response	No	NA	NA	Partial response	No
Partial response	Luminal	Partial response	Partial response	Yes	Partial response	Partial response	No response	No
Partial response	Luminal	Partial response	Partial response	Yes	Partial response	Partial response	No response	No
Partial response	Perianal	Partial response	Partial response	No	NA	NA	Partial response	No
Adverse events	Luminal	Remission	Remission	No	NA	NA	Remission	No
Adverse events	Perianal	Partial response	Partial response	No	NA	NA	Partial response	Yes
Adverse events	Luminal	Remission	Remission	No	NA	NA	Remission	Yes

ADA: Adalimumab; TNF: Tumour necrosis factor; IFX: Infliximab; NA: Not applicable; AE: Adverse events.

Citation: Chaparro M, Andreu M, Barreiro-de Acosta M, García-Planella E, Ricart E, Domènech E, Esteve M, Merino O, Nos P, Peñalva M, Gisbert JP. Effectiveness of infliximab after adalimumab failure in Crohn's disease. World J Gastroenterol 2012; 18(37): 5219-5224
URL: https://www.wjgnet.com/1007-9327/full/v18/i37/5219.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i37.5219