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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 7, 2012; 18(37): 5219-5224
Published online Oct 7, 2012. doi: 10.3748/wjg.v18.i37.5219
Published online Oct 7, 2012. doi: 10.3748/wjg.v18.i37.5219
Gender (female %) | 10 (67) |
Median age (yr) | 33 |
Time of evolution to adalimumab therapy (mo) | 69 |
Location | |
L1 | 7 (47) |
L2 | 1 (6) |
L3 | 7 (47) |
Behavior (%) | |
Inflammatory | 10 (67) |
Stricturing | 4 (27) |
Fistulizing | 1 (6) |
Perianal disease | 4 (27) |
Smoking habit | 3 (21) |
Previous surgical resection | 7 (47) |
Concomitant immunosuppressants | 11 (71) |
Reason for discontinuation of adalimumab | |
Partial response | 7 (47) |
Loss of efficacy | 5 (33) |
Adverse events | 3 (20) |
- Citation: Chaparro M, Andreu M, Barreiro-de Acosta M, García-Planella E, Ricart E, Domènech E, Esteve M, Merino O, Nos P, Peñalva M, Gisbert JP. Effectiveness of infliximab after adalimumab failure in Crohn's disease. World J Gastroenterol 2012; 18(37): 5219-5224
- URL: https://www.wjgnet.com/1007-9327/full/v18/i37/5219.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i37.5219