Serum levels of microRNAs can specifically predict liver injury of chronic hepatitis B

Table 3 Coefficient of Spearman correlation between microRNA variables and liver function parameter variables (all 68 samples)

Variables	miR-122	miR-638	miR-572	miR-575	miR-744
miR-122	1.000	0.757b	0.780b	0.614b	-0.669b
miR-638	0.757b	1.000	0.876b	0.822b	-0.733b
miR-572	0.780b	0.876b	1.000	0.794b	-0.639b
miR-575	0.614b	0.822b	0.794b	1.000	-0.570b
miR-744	-0.669b	-0.733b	-0.639b	-0.570b	1.000
ALT	0.559d	0.431d	0.375d	0.299c	-0.413d
AST	0.692d	0.474d	0.465d	0.324d	-0.434d
GGT	0.421d	0.371d	0.280c	0.214	-0.355d
ALP	0.358d	0.312d	0.320d	0.306c	-0.180
TBIL	0.034	0.041	-0.114	-0.074	-0.068
Bile acid	0.068	-0.020	0.008	-0.023	0.090

^bP < 0.01 microRNA (miRNA) vs miRNA without superscript b in the same column (2-tailed test);

^cP < 0.05 level miRNA vs liver function parameter (2-tailed test);

^dP < 0.01 level miRNA vs liver function parameter (2-tailed test). ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-glutamyltransferase; ALP: Alkaline phosphatase; TBIL: Total bilirubin and bile.