Serum levels of microRNAs can specifically predict liver injury of chronic hepatitis B

doi:10.3748/wjg.v18.i37.5188

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Oct 7, 2012 (publication date) through Feb 24, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2012; 18(37): 5188-5196
Published online Oct 7, 2012. doi: 10.3748/wjg.v18.i37.5188

Table 1 Clinical characteristics of participants in validation

Group	CHB	NASH	Ctrl
Individuals (n)	24	20	24
Gender (n)
Male	21	17	19
Female	3	3	5
Age (yr)	37.6 ± 9.0	39.4 ± 9.6	35.6 ± 10.2
ALT (IU/L)	82.6 (14-412)	51.7 (18-203)	21.5 (14-43)
AST (IU/L)	62.6 (9-206)	31.55 (17-62)	21.4 (16-49)
GGT (IU/L)	69.4 (10-580)	45.8 (13-124)	20.8 (12-33)
ALP (IU/L)	95.8 (51-211)	66.0 (41-90)	62.3 (42-96)
TBIL (μmol/L)	19.2 (10.2-50.7)	19.5 (13.1-31.7)	15.9 (6.9-27.1)
HBV DNA	7 377 395 (0-94 800 000)	0	0
Bile acid (μmol/L)	6.9 (1.4-13)	17.9 (3-118.7)	8.4 (4.1-12)
HBV status (n)
HBsAg⁺	24	0	0
HBsAg^-	0	20	24

Bile acid were given as medians (range). ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-glutamyltransferase; ALP: Alkaline phosphatase; TBIL: Total bilirubinand; CHB: Chronic hepatitis B; NASH: Nonalcohlic steatohepatitis; Ctrl: Healthy donor; HBsAg: Hepatitis B surface antigen.

Citation: Zhang H, Li QY, Guo ZZ, Guan Y, Du J, Lu YY, Hu YY, Liu P, Huang S, Su SB. Serum levels of microRNAs can specifically predict liver injury of chronic hepatitis B. World J Gastroenterol 2012; 18(37): 5188-5196
URL: https://www.wjgnet.com/1007-9327/full/v18/i37/5188.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i37.5188