Tumor necrosis factor alpha increases intestinal permeability in mice with fulminant hepatic failure

Figure 1 Systemic blood D(-)-lactate levels in the mouse model of fulminant hepatic failure and controls. Systemic blood D (-)-lactate levels 2, 6, 9, 12 and 24 h after injection in D-galactosamine (GalN)/lipopolysaccharide (LPS)-treated mice, and 6 h after injection in the saline, GalN, LPS, tumor necrosis factor alpha (TNF-α), anti-TNF-α immunoglobulin G antibody-pretreated groups. n = 5 rats for each time point. NS: Normal saline; FHF: Fulminant hepatic failure. The level of significance was set at ^aP < 0.05, ^bP < 0.01 vs baseline (NS group). Data are reported as the mean ± SD.