CpG island methylator phenotype and Helicobacter pylori infection associated with gastric cancer

doi:10.3748/wjg.v18.i36.5129

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Sep 28, 2012 (publication date) through Dec 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2012; 18(36): 5129-5134
Published online Sep 28, 2012. doi: 10.3748/wjg.v18.i36.5129

Table 2 Number of samples with methylated genes for gastric cancer, adjacent non-neoplastic tissue, and serum from gastric cancer patients and healthy controls

Gene	Tumor tissue	Serum from GC patients	Non-neoplastic tissues	Serum from healthy controls	χ²
Gene	(n = 75)	(n = 75)	(n = 72)	(n = 40)	χ²
APC	36^a	23	3	0	36.21
WIF- 1	43^a	26	4	0	45.28
DLC-1	38^a	22	3	0	39.49
DKK	41^a	24	2	0	47.79
SFRP-1	39^a	25	4	0	38.29
E-cad-1	36^a	20	3	0	36.21
RUNX-3	42^a	28	5	0	40.64

^aP < 0.05 vs the number of methylated gene promoters for tumor and non-neoplastic tissue samples with the χ² test. GC: Gastric cancer.

Citation: Liu JB, Wu XM, Cai J, Zhang JY, Zhang JL, Zhou SH, Shi MX, Qiang FL. CpG island methylator phenotype and Helicobacter pylori infection associated with gastric cancer. World J Gastroenterol 2012; 18(36): 5129-5134
URL: https://www.wjgnet.com/1007-9327/full/v18/i36/5129.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i36.5129