Coexistence of hyperlipidemia and acute cerebral ischemia/reperfusion induces severe liver damage in a rat model

Figure 3 Effect of hyperlipemia + ischemia/reperfusion on the level of serum pro-inflammatory cytokines after high-fat diet treatment for 18 wk and/or 2 h transient focal cerebral ischemia followed by 24 h reperfusion. Serum pro-inflammatory cytokines in the hyperlipemia (HL) + ischemia/reperfusion (I/R) group were significantly higher compared to those in other groups. A: Tumor necrosis factor (TNF)-α; B: Interleukin (IL)-1. Values are the mean ± SD. ^aP < 0.05, ^bP < 0.01 vs control group; ^cP < 0.05 vs HL group; ^fP < 0.01 vs I/R group.