Guidelines For Clinical Practice
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 21, 2012; 18(35): 4823-4854
Published online Sep 21, 2012. doi: 10.3748/wjg.v18.i35.4823
Table 4 Management of hepatitis B virus infection in inflammatory bowel disease patient being considered for tumor necrosis factor-α blockers therapy
Serology Management
HBsAg+, LE ↑Treat HBV
HbsAg+, normal LEVaccinate for HBV; monitor LE and HBV-DNA
HbsAg-Vaccinate for HBV
Consider giving a combined vaccination for HAV-HBVMeasure anti-HBs-Ab titer 1 mo after third injection to determine adequacy of response; additional doses may be necessary