Use of the tumor necrosis factor-blockers for Crohn's disease

doi:10.3748/wjg.v18.i35.4823

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2012; 18(35): 4823-4854
Published online Sep 21, 2012. doi: 10.3748/wjg.v18.i35.4823

Table 34 Benefits of mucosal healing in Crohn's disease[183]

Positive: IBSEN, Step-up/top-down, SONIC

IBSEN (Froslie): 5-yr longitudinal study of IBD patients not on TNFB and enjoying mucosal healing

CD: ↓ Inflammation, ↓ Future use of steroids

UC: ↓ Risk of future colectomy

Negative: Music

IBSEN: The inflammatory bowel south-eastern Norway (study group of gastroenterologists); SONIC: Study of biologic and immunomodulator naive patients in Crohn’s disease; TNFB: Tumor necrosis factor-α blockers; IBD: Inflammatory bowel disease; CD: Crohn's disease; UC: Ulcerative colitis.

Citation: Thomson AB, Gupta M, Freeman HJ. Use of the tumor necrosis factor-blockers for Crohn's disease. World J Gastroenterol 2012; 18(35): 4823-4854
URL: https://www.wjgnet.com/1007-9327/full/v18/i35/4823.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i35.4823