Use of the tumor necrosis factor-blockers for Crohn's disease

doi:10.3748/wjg.v18.i35.4823

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Sep 21, 2012 (publication date) through Nov 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2012; 18(35): 4823-4854
Published online Sep 21, 2012. doi: 10.3748/wjg.v18.i35.4823

Table 29 Rates of therapy-associated mucosal healing

Drug	CD		UC
	Week¹	MH, %	Week¹	MH, %
5-ASA			4-8	25-71
Prednisone	4-9	0-27
AZA	16-96	40-73	26	53-69
MTX	12-60	36-38
IFX	4-104	29-100	8-52	62-71
ADA	12	27	8	30
CER	10	5-55

¹Time for endoscopic assessment of mucosal healing. CD: Crohn's disease; UC: Ulcerative colitis; MH: Mucosal healing; 5-ASA: 5-Aminosalicylic acid; AZA: Azathioprine; MTX: Methotrexate; IFX: Infliximab; ADA: Adalimumab; CER: Certolizumab.

Citation: Thomson AB, Gupta M, Freeman HJ. Use of the tumor necrosis factor-blockers for Crohn's disease. World J Gastroenterol 2012; 18(35): 4823-4854
URL: https://www.wjgnet.com/1007-9327/full/v18/i35/4823.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i35.4823