Hyperthermia inhibits hypoxia-induced epithelial-mesenchymal transition in HepG2 hepatocellular carcinoma cells

Figure 1 Morphologic changes after hyperthermia or hypoxia treatment in HepG2 cells. A: Cells were cutured in 21% O₂ for 72 h; B: Cells were cultured in 1.0% O₂ for 72 h; C: Cells were treated with hyperthermia at 43 °C for 0.5 h, followed by treatment with normoxia; D: Cells were treated with hyperthermia at 43 °C for 0.5 h, followed by treatment with hypoxia.