Association of fucosyltransferase 2 gene variants with ulcerative colitis in Han and Uyghur patients in China

Table 3 Allelic association of four single nucleotide polymorphisms with ulcerative colitis in Han, Uyghur and combined populations

SNPs	Groups	Risk allele	Frequency (case/control)	χ2	Pobs	Pemp	OR (95% CI)	P (Q)	Poverall	OR (95% CI)
rs281377	Han	C	0.057/0.186	10.290	0.001	0.002	0.26 (0.11-0.63)	0.003	0.100	0.71 (0.47-1.07)
	Uyghur	C	0.327/0.299	0.270	0.603	0.636	1.14 (0.70-1.86)
rs1047781	Han	T	0.217/0.308	3.203	0.074	0.106	0.62 (0.37-1.05)	0.100	0.005	0.47 (0.31-0.72)
	Uyghur	T	0.082/0.235	10.950	0.001	0.002	0.29 (0.13-0.63)
rs601338	Han	A	0.009/0.090	7.954	0.005	0.102	0.10 (0.01-0.72)	0.140	0.0003	0.35 (0.21-0.58)
	Uyghur	A	0.214/0.389	9.979	0.002	0.002	0.43 (0.25-0.73)
rs602662	Han	A	0.028/0.028	0.000	0.985	1.000	1.01 (0.27-3.81)	0.860	0.680	0.90 (0.56-1.47)
	Uyghur	A	0.255/0.279	0.204	0.652	0.699	0.89 (0.53-1.49)

SNPs: Single nucleotide polymorphisms; Pobs: Observed P value, was calculated by 2 × 2 χ² test; Pemp: Pempirical, empirical null distribution of the association test P values; P(Q): Heterogeneity test, was calculated by Cochrane's Q test; Poverall: Meta-analysis P value, was calculated by Mantel–Haenszel test under fixed-effects or random-effects model; OR: Odd ratio; 95% CI: 95% confidential interval.