Primary biliary cirrhosis-specific autoantibodies in first degree relatives of Greek primary biliary cirrhosis patients

Table 1 Demographic characteristics of the study population

	Total	Male	Female	Age (yr)
PBC probands	44	4 (9.1)	40 (90.9)	58.8 ± 11.8
PBC FDRs	101	45 (44.6)	56 (55.4)	40.8 ± 17.9
Parents	9 (8.9)	5 (55.6)	4 (44.4)	72.8 ± 8.8
Children	69 (68.3)	30 (43.5)	39 (56.5)	31.3 ± 10.6
Siblings	23 (22.8)	10 (43.5)	13 (56.5)	56.7 ± 10.7
AIH-1 probands	11	2 (18.2)	9 (81.8)	48.8 ± 22.0
AIH-1 FDRs	21	12 (57.1)	9 (42.9)	37.2 ± 14.0
Parents	3 (14.3)	1 (33.3)	2 (66.7)	46.0 ± 19.3
Children	13 (61.9)	7 (53.8)	6 (46.2)	36.6 ± 10.3
Siblings	5 (23.8)	4 (80)	1 (20)	33.6 ± 20.0
PSC probands	7	4 (57.1)	3 (42.9)	40.7 ± 9.5
PSC FDRs	19	9 (47.4)	10 (52.6)	49.9 ± 21.0
Parents	9 (47.4)	4 (44.4)	5 (55.6)	67.4 ± 9.4
Children	4 (21.1)	2 (50)	2 (50)	17.8 ± 2.2
Siblings	6 (31.6)	3 (50)	3 (50)	45.0 ± 6.1
Healthy controls	40	17 (42.5)	23 (57.5)	43.1 ± 9.8

Data are shown as n (%) or mean ± SD. PBC: Primary biliary cirrhosis; AIH-1: Autoimmune hepatitis-1; PSC: Primary sclerosing cholangitis; FDRs: First-degree relatives.