7-difluoromethoxyl-5,4’-di-n-octylgenistein inhibits growth of gastric cancer cells through downregulating forkhead box M1

Figure 6 Forkhead box M1 small interfering RNA enhances the down-regulation of forkhead box M1 protein expression by 7-difluoromethoxyl-5,4’-di-n-octylgenistein and effects of forkhead box M1 small interfering RNA transfection or 7-difluoromethoxyl-5,4’-di-n-octylgenistein in AGS cell line. A: Western blotting analysis; B: The cell viability inhibitory effects of 7-difluoro methoxyl-5,4’-di-n-octylgenistein (DFOG) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylte trazolium bromide assay; C: Both on cell cycle distribution in AGS cells. ^aP < 0.05 vs treatment with dimethyl sulfoxide (DMSO); ^cP < 0.05 vs treatment with 5 μmol/L DFOG or forkhead box M1 (FOXM1) small interfering RNA (siRNA) alone.