Loss of fragile histidine triad and amplification of 1p36.22 and 11p15.5 in primary gastric adenocarcinomas

Figure 1 An overview of genomic imbalances in 20 primary gastric adenocarcinomas. The total number of gains was 180 (54 ≤ 1 Mb), and the total number of losses was 70 (16 ≤ 1 Mb). Partial or whole gains of 8q (12/20), 19q (8/20), and 20q (8/20) were most frequent. The most common amplicons were of the 11q13, 18q11.2 and 19q12 regions (green arrows). The loss of the FHIT gene and the partial loss of 4p with the smallest region of overlap including the PCDH7 gene were the most frequent losses (red arrow).