Development of a quantum-dot-labelled magnetic immunoassay method for circulating colorectal cancer cell detection

doi:10.3748/wjg.v18.i32.4419

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Aug 28, 2012 (publication date) through Feb 27, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2012; 18(32): 4419-4426
Published online Aug 28, 2012. doi: 10.3748/wjg.v18.i32.4419

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Figure 1 Circulating tumour cells are separated from the leucocytes using magnetic beads coupled with epithelial cell adhesion molecule antibody and a magnetic device. These complexes are then tagged with cytokeratin-19 (CK19) biotinylated antibody and streptavidin-conjugated quantum dots (QDs) which lead to the detection of a fluorescent signal. EpCAM: Epithelial cell adhesion molecule; DLD-1: Human colon adenocarcinoma cell line.

Citation: Gazouli M, Lyberopoulou A, Pericleous P, Rizos S, Aravantinos G, Nikiteas N, Anagnou NP, Efstathopoulos EP. Development of a quantum-dot-labelled magnetic immunoassay method for circulating colorectal cancer cell detection. World J Gastroenterol 2012; 18(32): 4419-4426
URL: https://www.wjgnet.com/1007-9327/full/v18/i32/4419.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i32.4419