Gene expression profiling and endothelin in acute experimental pancreatitis

Figure 7 Immunohistochemical analysis of the localization of endothelin-A and endothelin-B receptors in dorsal root ganglia from naïve or pancreatitic rats. A: Naïve endothelin (ET)-A; B: Dibutyltin dichloride (DBTC) ET-A; C: Naïve ET-B; D, E: DBTC ET-B (n = 5). ET-A receptor expression is shown in primary sensory neurons (A, B). In contrast, ET-B receptors (B-E) are primarily localized on the Schwann cells (myelin sheaths) surrounding the axons passing through the dorsal root ganglia from naïve or pancreatitic rats (4’,6-diamidino-2-phenylindole nuclear blue staining and Alexa Fluor 568, red).