Tissue transglutaminase levels above 100 U/mL and celiac disease: A prospective study

doi:10.3748/wjg.v18.i32.4399

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Aug 28, 2012 (publication date) through Feb 27, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2012; 18(32): 4399-4403
Published online Aug 28, 2012. doi: 10.3748/wjg.v18.i32.4399

Table 2 Sensitivity, specificity, positive predictive value and negative predictive value of anti-endomysium antibodies and anti-tissue-transglutaminase antibodies (%)

	Sensitivity	Specificity	PPV	NPV
IgA EMA	97 (91-99)	68 (55-79)	85 (78-90)	91 (79-97)
IgA tTGA >10	97 (91-99)	78 (65-87)	89 (82-94)	92 (81-98)
IgA tTGA ≥ 100	73 (63-80)	100 (93-100)	100 (95-100)	66 (55-75)

The 95% CI are given in parentheses. IgA: Immunoglobulin A; EMA: Anti-endomysium antibodies; tTGA: Anti-tissue-transglutaminase antibodies; PPV: Positive predictive value; NPV: Negative predictive value.

Citation: Mubarak A, Wolters VM, Gmelig-Meyling FH, ten Kate FJ, Houwen RH. Tissue transglutaminase levels above 100 U/mL and celiac disease: A prospective study. World J Gastroenterol 2012; 18(32): 4399-4403
URL: https://www.wjgnet.com/1007-9327/full/v18/i32/4399.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i32.4399