How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related?

Table 4 Correlation between multichannel intraluminal impedance and pH analysis and the reflux finding score/ reflux symptom index analysis

	ERD/NERD	HE	No GERD1	P value
AET (%)	7.4 ± 3.2	3.5 ± 1.7	1.9 ± 0.8	< 0.05
Reflux number (n)	103.2 ± 12.1	44.7 ± 6.2	35.1 ± 7.4	< 0.05
Proximal refluxes (mean %)	31	29	18	< 0.05
Acid refluxes (n)	62.5 ± 15.4	32.9 ± 5.1	19.7 ± 6.2	< 0.05
Non-acid refluxes (n)	40.1 ± 7.6	13.1 ± 4.4	15.8 ± 4.9	< 0.05
Gas refluxes (n)	11.6 ± 9.7	13.1 ± 8.1	21.7 ± 15.3	< 0.05
SAP/SI	Positive	Positive	Negative	-
RFS	10.9 ± 3.3	9.1 ± 2.7	7.6 ± 3.1	NS
RSI	14.3 ± 5.2	16.3 ± 4.7	15.8 ± 4.9	NS

¹Patients with normal acid exposure time and without correlation between symptoms and refluxes. AET: Acid exposure time; ERD: Erosive esophagitis; NERD: Non erosive esophagitis; HE: Hypersensitive esophagus. SAP/SI: Symptom association probability/symptom index; RFS: Reflux finding score; RSI: Reflux symptom index; NS: Not statistically significant.