How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related?

Table 1 Results of the gastroesophageal reflux disease impact scale questionnaire before and after proton pump inhibitor therapy

How often have you had the following symptoms: (GIS questionnaire)	Before PPI therapy				After PPI therapy				P value
	Always	Often	Sometimes	Never	Always	Often	Sometimes	Never
Pain in your chest or behind the breastbone?	1	0	0	0	0	0	1	0	NS
Burning sensation in your chest or behind the breastbone?	10	4	1	0	3	1	1	10	< 0.05
Regurgitation or acid taste in your mouth?	2	5	2	0	1	1	3	4	< 0.05
Pain or burning in your upper stomach?	1	2	2	0	0	1	1	3	< 0.05
Sore throat or hoarseness that is related to your heartburn or acid reflux?	27	5	9	0	23	8	6	4	NS

NS: Not statistically significant; GIS: Gastroesophageal reflux disease impact scale; PPI: Proton pump inhibitor.