Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells

doi:10.3748/wjg.v18.i31.4199

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Aug 21, 2012 (publication date) through Dec 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 21, 2012; 18(31): 4199-4206
Published online Aug 21, 2012. doi: 10.3748/wjg.v18.i31.4199

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Figure 3 Oxymatrine liposomes inhibited fibrosis-related gene expression. The expression of fibrosis-related gene, such as MMP-2, TIMP-1 and collagen I was evaluated by real-time polymerase chain reaction. ^aP < 0.05 vs normal; ^cP < 0.05 vs CCl₄-induced heaptic fibrosis; ^eP < 0.05 vs oxymatrine liposomes. MMP: Matrix metallopeptidase; TIMP: Tissue inhibitor of metalloproteinase; OM: Oxymatrine; RGD: Arg-Gly-Asp.

Citation: Chai NL, Fu Q, Shi H, Cai CH, Wan J, Xu SP, Wu BY. Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells. World J Gastroenterol 2012; 18(31): 4199-4206
URL: https://www.wjgnet.com/1007-9327/full/v18/i31/4199.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i31.4199