siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin

Figure 3 Expression of proteins in esophageal squamous cancer cells TE13 and compared with control. A: Expression analysis of protein kinase B (pAkt), total Akt, protein Glycogen synthase kinase 3β (pGSK3β), pRaf, protein Phosphoinositide-dependent kinase-1 (pPDK1), phosphatase and tensin homolog (pPTEN), nuclear factor-κB (NF-κB) and cyclin D1 proteins compared in esophageal squamous cancer cells TE13. Lane 1: Mock; Lane 2: Scrambled (non-target siRNA); Lane 3: TC21 siRNA transfected for 48 h; Lane 4: TC21 siRNA transfected for 72 h; B: Bar diagram showing relative levels of proteins in comparison with control protein GAPDH. GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.