Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer

doi:10.3748/wjg.v18.i30.4037

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Aug 14, 2012 (publication date) through Feb 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 14, 2012; 18(30): 4037-4043
Published online Aug 14, 2012. doi: 10.3748/wjg.v18.i30.4037

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Figure 2 Representative images from immunohistochemistry assays of 368 archived gastric cancer cases at 20 × 10 magnification. A: Moderately differentiated adenocarcinoma and negative for the M2 isoform of pyruvate kinase (PKM2) expression; B: Signet ring cell carcinoma and negative for PKM2 expression; C: Moderately differentiated adenocarcinoma and positive for PKM2 expression; D: Signet ring cell carcinoma and positive for PKM2 expression.

Citation: Lim JY, Yoon SO, Seol SY, Hong SW, Kim JW, Choi SH, Cho JY. Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer. World J Gastroenterol 2012; 18(30): 4037-4043
URL: https://www.wjgnet.com/1007-9327/full/v18/i30/4037.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i30.4037