Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer

Table 1 Relationships between human papilloma virus 16 infection and clinical parameters of colorectal cancer patients n (%)

Parameters	HPV16
	Negative	Positive	P value
Gender			0.782
Male (n = 35)	29 (82.9)	6 (17.1)
Female (n = 34)	29 (85.3)	5 (14.7)
Age (yr)			0.322
< 68 (n = 31)	28 (90.3)	3 (9.7)
> 68 (n = 38)	30 (78.9)	8 (21.1)
Smoking status			0.718
No (n = 49)	42 (85.7)	7 (14.3)
Yes (n = 20)	16 (80.0)	4 (20.0)
Stage			0.017
I (n = 6)	2(33.3)	4 (66.7)
II (n = 24)	21 (87.5)	3 (12.5)
III (n = 21)	19 (90.5)	2 (9.5)
IV (n = 18)	16 (88.9)	2 (11.1)
Tumor site			0.554
Ascending colon (n = 22)	19 (86.4)	3 (13.6)
Transverse colon (n = 5)	5 (100.0)	0 (0)
Descending colon (n = 5)	3 (60.0)	2 (40.0)
Sigmoid colon (n = 10)	9 (90.0)	1 (10.0)
Rectum (n = 27)	22 (81.5)	5 (18.5)

HPV: Human papilloma virus.