1H NMR-based serum metabolic profiling in compensated and decompensated cirrhosis

Figure 3 Multivariate modeling of compensated and decompensated liver cirrhosis patients. A: Principal component analysis score plot of the serum ¹H nuclear magnetic resonance spectra from compensated liver cirrhosis (LC) (squares) and decompensated LC (black dots) patients. B: Orthogonal partial least-squares discriminant analysis (OPLS-DA) score plot of compensated LC (squares) and decompensated LC (dots) patients; C: Corresponding coefficient loading plots for the discrimination of the OPLS-DA model; D: Validation tests of the discriminatory power using the OPLS-DA model. Twenty cirrhotic patients were selected randomly and included 10 compensated LC (empty squares) and 10 decompensated LC (empty dots) patients.