1H NMR-based serum metabolic profiling in compensated and decompensated cirrhosis

Table 2 Orthogonal partial least-squares discriminant analysis coefficients derived from the nuclear magnetic resonance data of metabolites in serum obtained from compensated and decompensated cirrhosis patients

Metabolites	δ1H	Correlation coefficients
		Compensated LC	Decompensated LC
β-Glucose	3.24, 4.65	0.654	0.722
α-Glucose	3.425.24	0.602	0.806
CH3-(CH2)n-(LDL&VLDL)	1.28	0.748	-0.693
Valine	0.99, 1.04	-0.903	-0.910
Tyrosine	6.89, 7.19	0.675	0.805
Succinate	2.40	-	0.603
Pyruvate	2.37	-	0.585
Phenylalanine	7.32, 7.41	-	0.749
NAG:N-acetyl glycoprotein	2.04	-0.583	-0.774
Lysine	1.72, 3.01, 3.78	-0.602	-
Lipid, H3-(CH2)n-(LDL&VLDL)	0.86	0.805	-0.793
Leucine	0.93	-0.876	-0.727
Lactate	1.33, 4.12	-0.671	-0.769
Isoleucine	0.96, 1.01	-0.916	-0.859
Histidine	7.06, 7.75	-	0.616
GPC/PC	3.21, 3.35	-0.732	-0.712
Glutamine	2.14, 2.45, 3.78	-0.659	0.706
Glutamate	2.03, 2.35, 3.78	-	0.554
Creatine	3.04, 3.93	-0.709	0.555
Citrate	2.53, 2.67	0.657	0.604
Alanine	1.48	-	0.571
Acetone	2.23	0.729	-

The positive and negative signs indicate a positive and negative correlation in the concentrations, respectively. “-”: The |correlation coefficient| is less than 0.355.