Aging is a risk factor of nonalcoholic fatty liver disease in premenopausal women

Table 6 Adjusted associations between nonalcoholic fatty liver disease and age in 855 premenopausal women and 392 postmenopausal women

	Premenopausal subjects (n = 855)		Postmenopausal subjects (n = 392)
	Adjusted odds ratio (95% CI)	P Value	Adjusted odds ratio (95% CI)	P Value
Age	1.12 (1.05–1.2)	0.001	1 (0.93–1.07)	0.91
Presence of metabolic syndrome at baseline	43.06 (12.66–146.51)	< 0.001	4.87 (1.29–18.34)	0.019
Weight gain	1.76 (1.4–2.21)	< 0.001	1.67 (1.27–2.21)	< 0.001

We applied a multivariate logistic regression model to calculate the odds ratio for age for development of nonalcoholic fatty liver disease after adjusting for weight gain and metabolic syndrome. After completing follow-up examinations, 1247 women who received no hormone replacement therapy were divided into pre- or postmenopausal groups. CI: Confidence interval.