Aging is a risk factor of nonalcoholic fatty liver disease in premenopausal women

Table 3 The association of baseline characteristics with nonalcoholic fatty liver disease in pre- or postmenopausal women

	Premenopausal women (n = 1023)			Postmenopausal women (n = 549)
	Normal US	NAFLD	P Value	Normal US	NAFLD	P Value
Number of subjects (%)	962	61 (6)		468	81 (15)
Mean age ± SD, yr	42.2 (6.4)	44.7 (6.1)	0.003	56 (5.5)	55.9 (5.4)	0.874
Number (%) who met a criterion of metabolic syndrome
Body mass index	75 (8)	32 (52)	< 0.001	37 (8)	43 (53)	< 0.001
Glucose	24 (2)	15 (25)	< 0.001	25 (5)	8 (10)	< 0.001
Blood pressure	94 (10)	21 (34)	< 0.001	104 (22)	35 (43)	< 0.001
HDL-cholesterol	221 (23)	31 (51)	< 0.001	128 (27)	48 (59)	< 0.001
Triglycerides	29 (3)	13 (21)	< 0.001	36 (8)	21 (26)	< 0.001
Number (%) who met ≥3 criteria of metabolic syndrome	18 (2)	17 (28)	< 0.001	26 (6)	23 (28)	< 0.001
Number (%) light-drinkers	472 (49.1)	24 (3.9)	0.15	190 (40.6)	34 (42.0)	0.81
Number (%) current smokers	48 (5.0)	4 (6.6)	0.54	34 (7.3)	5 (6.2)	0.64
Number (%) ex-smokers	103 (1.1)	5 (8.2)	0.67	50 (10.7)	5 (6.2)	0.31
Number (%) regular exercisers	181 (18.8)	8 (13.1)	0.31	105 (22.4)	15 (18.5)	0.47

This table summarizes the baseline data of 1572 women, excluding 257 subjects with hormone replacement therapy. We separated the subjects into pre- or postmenopausal groups. US: Abdominal ultrasonography; NAFLD: Nonalcoholic fatty liver disease; HDL: High-density lipoprotein.