Aging is a risk factor of nonalcoholic fatty liver disease in premenopausal women

Table 2 Unadjusted and adjusted associations between nonalcoholic fatty liver disease and age, menopause status, hormone replacement therapy, and metabolic syndrome in 1829 women

	Unadjusted odds ratio (95% CI)	P values	Adjusted odds ratio (95% CI)	P values
Age	1.06 (1.04-1.08)	< 0.001	1.03 (1-1.06)	0.027
Postmenopausal state	2.73 (1.92-3.87)	< 0.001	1.55 (0.92-2.61)	0.096
Active hormone replacement therapy	2.57 (1.66-3.97)	< 0.001	1.54 (0.93-2.54)	0.092
Presence of metabolic syndrome at baseline	12.52 (8.03-19.51)	< 0.001	11.28 (7.04-18.06)	< 0.001

We calculated the odds ratio of each factor for nonalcoholic fatty liver disease in a univariate logistic regression model. The columns to the left indicate unadjusted odds ratio [95% confidence interval (CI)]. We selected all parameters as cofactors in a multivariate logistic regression model. The columns to the right indicate adjusted odds ratio (95% CI).