Risk of post-operative complications associated with anti-TNF therapy in inflammatory bowel disease

Table 3 Post-operative risks of complications with Crohn’s disease

Authors	Complications	Cases (%)	Controls (%)	Risks of complications, OR (95% CI)
Marchal[22]	Early Minor (10 d)	15	13	1.2 (0.3-4.3)
	Late Minor (3 mo)	2.50	5.10	1.1 (0.3-4.0)
	Early Major (10 d)	12.50	7.70	1.7 (0.3-7.7)
	Late Major (3 mo)	17.50	12.80	1.4 (0.4-5.0)
Colombel[23]	Septic	17		0.9 (0.4-1.9)
	Non-septic	23		1.0 (0.5-2.0)
Appau[24]	30 d readmission	20	9.4 + 2.9	2.3 (1.0-5.3)
	30 d sepsis	20	9.7 + 5.8	2.6 (1.1-6.1)
	30 d intra-abdominal abscess	10	4.3 + 4.3 (Non IFX + pre IFX group)	5.8 (1.7-19.7)
Kunitake[29] (combined study)	Post-operative cumulative complications	16.80	15.70	1.1 (0.6-2.0)

IFX: Infliximab; OR: Odd ratio; CI: Confidence interval.