Mutual regulation between microRNA-373 and methyl-CpG-binding domain protein 2 in hilar cholangiocarcinoma

Figure 1 Expression of miR-373 and the association with clinicopathological factors in patients with hilar cholangiocarcinoma. A: Representative expression of miR-373 decreased in tumor and in QBC₉₃₉ detected by RT-PCR (^aP < 0.05 vs control); B: Taqman microRNA assay of miR-373 displayed 2.94-fold down-regulation in tumor group (^bP < 0.01 vs control); C: Relationship between miR-373 expression and overall survival in the patients with hilar cholangiocarcinoma. The median overall survival time was 16.3 mo and 29.7 mo in low- and high- miR-373 group, respectively ^cP < 0.05 vs high-group; D: Kaplan-Meier disease-free survival, the median disease-free survival time were 11.2 mo, 23.4 mo in low- and high- miR-373 group, respectively (^eP < 0.05 vs high-group).