Choice of approach for hepatectomy for hepatocellular carcinoma located in the caudate lobe: Isolated or combined lobectomy?

Table 4 Multivariate analysis

Variables	Hazard ratio	95% CI	P value
Overall survival
Absence of cancer spread1	0.44	0.24-0.69	0.007
Child-Pugh class A	0.86	0.66-1.33	0.17
Combined resection	0.57	0.32-0.92	0.04
Tumor size < 30 mm	0.61	0.32-1.05	0.08
Total bilirubin < 1 mg/dL	0.52	0.28-1.06	0.07
α-Fetoprotein < 100 ng/mL	0.61	0.33-1.19	0.07
Disease-free survival
Absence of cancer spread1	0.61	0.37-0.82	0.001
Combined resection	0.66	0.42-0.94	0.03
Negative tumor exposure	0.39	0.20-0.77	0.04
Total bilirubin < 1 mg/dL	0.56	0.37-0.89	0.02

¹Cancer spread was defined by presence of microscopic vascular invasion and/or intrahepatic metastasis.