Study of human B7 homolog 1 expression in patients with hepatitis B virus infection

Figure 9 The analysis of the effects of hepatitis B surface antigen on intracellular interferon-γ production. A: Representative plots of intracellular interferon-γ (IFN-γ) produced by CD8+ T cells in mixed leucocyte reaction (MLRs) with or without hepatitis B surface antigen (HBsAg) pretreatment. Values in the upper right quadrant indicate the percentage of IFN-γ positive CD8+ T cells; B: In MLRs system at ratios of 1:5 and 1:10 R/S, IFN-γ production by CD8+T cells was reduced significantly by HBsAg pretreatment (at ratios of 1:5 and 1:10 R/S, P < 0.001, n = 3). R/S: Responder cell-stimulator cell.