Study of human B7 homolog 1 expression in patients with hepatitis B virus infection

Figure 1 Circulating human B7 homolog 1 expression comparison among acute hepatitis B, chronic hepatitis B virus tolerance and autoimmune hepatitis patients. A: Representative dot plots of double measurements of fifteen independent experiments; B: B7 homolog 1 (B7-H1) expression level on circulating myeloid dendritic cells (mDCs) of acute hepatitis B (AHB) patients was significantly higher than that in chronic hepatitis B virus tolerance (CHB-T) patients (n = 12, P < 0.05). Autoimmune hepatitis (AIH) patients exhibited the highest levels of B7-H1 expression on circulating mDCs among these groups (n = 3, P < 0.05); C: In AHB patients, there was significant, positive correlation between B7-H1 expression on mDCs and serum alanine aminotransferase (ALT) levels in AHB patients (r = 0.809). HC: Healthy controls.